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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09216dd7f219ef5398e07b2936cc98c832d14aa876a42ca4bf1df5a3e7de075c' 
  AND token = 'v2T+ani2sycbiOwtj/eXl8uUIrllYRWKY38Icm6Upjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}