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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c66c662d97a8bb1faf286627b8b454fbcc8b494ea2906875a47b603e79662cb' 
  AND token = 'JurGzSyP0Om7ZnbQZVWm87TcsJMC4OftsspvNG0zIug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}