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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43f6c2e8460f6e641a7d6058183f2eb6e640d6c72fa036ad6377fed3d29b44a' 
  AND token = 'C+efgZmv4WkUVAdkEj8db8ZXrzsq2B/X8FPF2Z2lRsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}