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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5337f0ae0027a845206341c67ae8848ddea6bef6e1d4f004b9f17d0a0c86268' 
  AND token = 'hqYH2PIGMKROTjein6VJccuHD3POPxRMOtaodC3qJiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}