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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04bfb072fa395ea27416dc8a2528f2ef91e8d36cd8cc87bcb361b4f0e195bf5b' 
  AND token = 'TPCPY2CywxQVScVdcfgIt+f4ETqncHhHo1nH2A3l6uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}