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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '123e68d45c075a9d2e8c1dac1713d0e4be7b6e27e27d56f5e1f9e37686dc0539' 
  AND token = '8oI0+78enADwAHI7RTbrBlc5AM3MIklB0Bn7rmLyrts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}