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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f58e88c980f176315fa414bcab32c68e5117677cfc51f88860e8ed5443b3b751' 
  AND token = '/EWxegeWfX7NBMfg7wFsV+v/0GvAdonnE7zPpOgMVY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}