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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd7ba411add04967cc9fb9c04fc0dfe9678822d95d3d621604f4ccda8aa18d3' 
  AND token = '3Qp2essPA09MGf3gng+ewi+uqcRPq7Ki1TrgCuOCAko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}