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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a431bc16aa625cc61996c84100933f975ee5cfec90226d8a6bbb4058fd6604' 
  AND token = 'jdwKPF0oeaurgpjJfJ1RUfS2zc76J/TTxMn6aolm4Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}