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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fa8bc0c359d956b3779446602b7becfa9ea489d7355aa2607d72c587f4256fe' 
  AND token = '9OVvOLfUDf14sKuM4efZb40pOXW6pDs2eEg/MJ5xWy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}