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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '008bed26e7d1ec7619de2cb519a6756158e12de8a34c2520ea1d11bc919df2bc' 
  AND token = 'j4SxkzV/1hQsdH5QPNNyN1ENgtD9F/bnoVGQsFrGxfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}