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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '676e561c37318e1688ee4094e8e1b4915912b1934c506d468490ea6dcab06e05' 
  AND token = 'np6o8s6uOuultnXIrzCz1G5QQ21TbDrY8hW6paDn4SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}