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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '282d5be071c6b97177f2956dc30645b99808d00ab3d04737a80eb02b5281b7f7' 
  AND token = '4niZHzY+iJ3vz+LL+6WTMVzaYXmChYr5ZM88uIykxdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}