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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '839a1f8a54b368be1fd74fa887a02d1baad8b4c8f24dcedb13eea943622ab334' 
  AND token = 'NYjEHYk/a2dnUaKQTRsA2OQNXBxedaV50LQEBfQFXjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}