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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d94f7825c08f5c8703e28af70b4fd6604a7a9db03b9072c3cec74593783c341' 
  AND token = '+RZeZX6Pn0YiWz6F09q+CL5ApLHakXjFCg4PwotxoFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}