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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '959dccadcee66e4f838ce8cfc248c28f52c33f1d35e23f5a0e73597ef3c2604c' 
  AND token = '0GL6T2XH3m9TkhlOEFCfwhqEIn/0h5mv0iZGN7eVGZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}