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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31ca0bb87b2b870660557719dd2a9bbb1c13db62b2ee627465d196e28e0b30e3' 
  AND token = '9TB+zAUG+yWefvwyU/h0UVpuTINLuWhJLVSlK664MEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}