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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1c8d35b6e2ecc6b5b5c4d64d570272a243ad8455f25f929541ea13f24c049cc' 
  AND token = 'LQOjuFtqDQqZs4IX32apF5eV8CooKNKk/kLnNJAk5k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}