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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85d8e9bb9bc6d78155c2779031925349f80dbf3b4196ed1762a5b46fd70c3556' 
  AND token = 'tAQi3Klg1daneSD0nDIbP4XJD9RECPXHhcTJJO1zsbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}