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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '212793fde1c1bc4ca1109c02d211505f6d8566b729efc93cafc82d670d473214' 
  AND token = 'aEkx8cWU9A12QosWDQpJU9/1LcDVtPPzz//I8aGAB8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}