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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38d7bcae4570151e5a0497383c0e48398387c6cb6efe827f54771aba16c3bbb' 
  AND token = 'YhsaeSXsJ0TPuOE6EUCq4shQTW1koWAoqQ1ziZtGPIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}