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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341eb68f8ccb0e19e77a553c702625217df6a5515b1de713cb5c66a6b4e7a412' 
  AND token = 'f9p6uADLNFtymMLnNgEGJFWwtvVh1LpvR+dcp+0Lt74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}