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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424afe26fb44910846488cb0c6e79db73e4ba936fb52574f61eeddaec984f168' 
  AND token = 'gSquvd6UV3GDXAZ8qfK3hWpvGCeWAfSCpyZaK+eP1OE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}