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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c7117f0a7f74772506e6d9b2d69d914dfd1442e6b028f96b9fb8c841496121' 
  AND token = 'IKQMechCafrtCeV+7pirxdd5zOUN0c7caZ8M6EHRfss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}