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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b654f782a5ccecf60d95ae27d362d7598afaf4f8c09f9990b907323930a59a' 
  AND token = '+DzVx76VVNH+50L+X5ZNKJE1UwNkJ+0jPn9EY6c06Bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}