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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfa32937729a1a037a3ee0ee28c267630674935b021dee3bf657e20bb440d06e' 
  AND token = 'zpoCvXDxx6BU0S68TUN5v+2aX+0VnzlBgfZERUn1z6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}