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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ccd1c10f15274694785f1c8dfe645aa915777ad2564c54e1af0a442c4e6a39' 
  AND token = '6PcPrIwRAx0GWcx6a6f06nS9At+XpSCeIauikhJ6SwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}