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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '922a8c27f7368d71ac90f6c98c9488efbc557e4de1470263ece4019930f147db' 
  AND token = 's6gp/ULrSc4n+3kgq07FPvKuM+IL2WzyKmLmDfX7nP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}