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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a6347607c18dfecdc18c8d439e5f290dc45021f3b86a6c2c1180436ada1a55' 
  AND token = 'hELf+L/wNM1TzwTVgc5pL2T966y4AbOaVoJLxoAZzmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}