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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f3e8898e9e68967ef77cc0c92665e7eff23c5c1e4e6bbdc8b245ab08b481fe' 
  AND token = 't2stPDhgCtYghA+8tMem+3UvMi9UjU0yxVUhd7Tl5c0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}