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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0517a28e3fc8446d6c123654b2327874676cb15a79b907550abda0a08db14f' 
  AND token = '3G8ALVA/wt5DKoAP2p+/dA/5X1dqcD6xTpSzQZB/TOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}