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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '739a0bf52380235f8462f401442e797c1628f1289b12f49e6a7a028ac01c52bd' 
  AND token = '7a5SwfwuM2TGcihMXvR85T2Vd8gbaVDjWzneYgn13Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}