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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80b185c112779e7b650149e5c9471c9ad248e082e33dbe8d6345c6b23168d4f' 
  AND token = 'OQsW3UGreA3ANWea7Wl69HjviZNaW0k/drTBp04hTBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}