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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e6f5ab472232a1fd2772e305e480a0ac529d4821ab4f0bffde139e1149b4cf1' 
  AND token = 'oNStRNeRF0yzz1NWEyQHVPaBRm/03R2O9JemNLxEkFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}