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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd099138cde15ca3f98d315e01f7dad5e0c08de250715ed7bcb0bf6605d8b3ec' 
  AND token = 'XUgL4uxGL1RHjvAZg5TjFQAm1CIftoYli4atoFW/NC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}