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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d77a6c8c1129fa1f2c68a62f3f8cb04f185e2fb11dc75ef7566866f2e6a2b30' 
  AND token = '1+mHNEkOEUXvncCMeXE/6LypGNnAt+0QfvbwnEl2d74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}