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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd268269a552de3672212236a1f3a061ed6ea63893620ebe47e47bcebd3f10b21' 
  AND token = 'TcWO55P5ON2HvmbCbd6AYFF+1CBaNs99Ikjfx1kolxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}