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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef3f0d014a40d81d809014f3e46c7062a4bf782e00509dc7bb61fc191e527ae' 
  AND token = 'zdtp9CoA8BtoiYONKrQYSyuTFhLXV2qAKmIAh7RcY3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}