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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '338122a2fe84e8798857a1d42c4c05d2a910b079a6569df607e2cc721fa56b53' 
  AND token = 'NbCwNz4OSTNHF9W9CHi7PUNqcwmlpmLNVs7Y/f87OY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}