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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef74bdd3b0e3ed05ef8fcd2447acb91c4181880a9c17cf3015e994d50047df45' 
  AND token = 'rDaHmWvHIN5/se2Znr49JHQXtdnvvaMHtmAT+pnYLlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}