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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20e046a49f32c5754246d33f2cc8ac913ac70adf2a6f2ec1d18cb6a70cd32437' 
  AND token = 'GnSeJ2GF79MKeJep5vc9fPdec6niR1Qi95xCbRSO4YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}