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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46112ea22e1ac7855acf4ab12e3ae5b0e0a5a0c60c319609b63e8f65500ff645' 
  AND token = 'DT/wKjXY9+NkzGwpAER9RDRWr/epImVq6MSn1wcfTP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}