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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def8e18f6e5cee5c63b54153ea219c5ad44525aaa4fe07fda994a50fb688b8cd' 
  AND token = '/99QurOO70ajSWr3Oir98b/wP1/mkMQllw6XDKws0Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}