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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2baec6c9e39a0a340211b1c3c1375bb586670e9fcff5e77be9e22bc6834ba78a' 
  AND token = '/Q5PWvOAAWPxgZfkj6he5LmE7nitKz6Xa/MjFgtH4d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}