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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48aca97f395e08e5e5c2e6c7506836f5e5cc9b411e1ae599a8a8032dc99f904a' 
  AND token = 'v7bZEy6RWM01nE2QrJEO/YN8g7GZtNFZTxKRGA1g+Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}