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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5527c89a95635f74d5b85ea1e9bfe3ac98a2ec00be73979b62d384abf8d8503' 
  AND token = 'DARFpylzcAj2LClhLT5UZ37cREPMzeJZfiZIVNQA6f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}