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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9973180449ca33a5e3fd4b2294b55cf27bdb7d0a0d02583459f69a0df0334e6c' 
  AND token = '40wvwJlcy5X13ntUgFwoQl/QBkigfhsUs0I8UZH/Vg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}