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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa3d1a456349305f2f24655769ba6a9cc63866b38da8ce321847c060fb10b707' 
  AND token = 'drW3Lz0hIch9nfQGDRkIbEa+auDLH1NzpmyLXfI0sk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}