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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a299fd82574b5e686187e1357d017d05da662a561c01afedb9d52dd20bd5463' 
  AND token = 'oIM9Y9lNDtS9LzWGM78kS5rbHO9qENN9wiUbEjV1PzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}