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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb8c5604ab858e4206912a081bdcaf6ee1e3ebf7f91e22d45a4442012a705972' 
  AND token = 'e1mZ6EEfuQpeE9sA4lkmf2l8TBO06XsEh1kAuPvnarg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}